醫學研究 學術文章 Prevalence of unruptured intracranial aneurysms in the Hong Kong general population and comparison with inididuals with symptoms or history of cardiovascular disease. Yu SCH, Cheng PW, Antonio GE, Chan SCC, Lau TWW, Ma HTG. Hong Kong Med J. 2022 Feb;28(1):16-23. doi: 10.12809/hkmj209236. PMID: 35260496.腦血管病變 Cerebrovascular disease /中風 Stroke
Prevalence of unruptured intracranial aneurysms in the Hong Kong general population and comparison with inididuals with symptoms or history of cardiovascular disease
Yu SCH, Cheng PW, Antonio GE, Chan SCC, Lau TWW, Ma HTG. Hong Kong Med J. 2022 Feb;28(1):16-23. doi: 10.12809/hkmj209236. PMID: 35260496.
Abstract
Introduction: We aimed to estimate the prevalence of unruptured intracranial aneurysms among the general population in Hong Kong, which has not yet been determined; we also estimated its prevalence among individuals who have symptoms or history of cerebrovascular disease.
Methods: This retrospective cross-sectional study included the first cerebral magnetic resonance angiography (MRA) records of Hong Kong citizens who underwent MRA in a single hospital between July 1994 and December 2009. Records were excluded for individuals with repeat examination or a personal/family history of intracranial aneurysm. The overall prevalence of unruptured intracranial aneurysms in Hong Kong was estimated from the sex- and age-specific prevalences in the General group, as well as census data regarding the sex and age composition of the Hong Kong population.
Results: In total, data on 6637 individuals were included. Asymptomatic individuals were assumed to represent the general public and allocated into a General group (n=3597); the remaining individuals were allocated into a Symptom group (n=2409) or a cerebrovascular disease (CVD) group (n=707). The prevalence of unruptured intracranial aneurysms was significantly lower in the General group (176/3597, 4.9%) than in the Symptom group (152/2409, 6.3%; P=0.018). The prevalences in women and men were 5.9% (107/1809) and 3.9% (69/1788), respectively, in the General group (P=0.004). These prevalences generally increased with age. The prevalences did not significantly differ between the General and CVD groups.
Conclusions: The estimated overall prevalence of unruptured intracranial aneurysm in the Hong Kong population was 3.6%. The prevalence of unruptured intracranial aneurysm was significantly higher in the Symptom group than in the General group.
Citation:
Yu SCH, Cheng PW, Antonio GE, Chan SCC, Lau TWW, Ma HTG. Prevalence of unruptured intracranial aneurysms in the Hong Kong general population and comparison with individuals with symptoms or history of cerebrovascular disease. Hong Kong Med J. 2022 Feb;28(1):16-23. doi: 10.12809/hkmj209236. PMID: 35260496.